Tiny newborns face bigger lung risks, Abu Dhabi hospital study shows

Extremely small size at birth continues to signal which premature babies will face the most dangerous respiratory complications, according to a new neonatal study out of SEHA’s Corniche Hospital that tracked 161 infants delivered before the 32-week mark.

Researchers found that the tiniest newborns—those with severe chronic lung disease—needed extended periods on ventilators and supplemental oxygen, and carried a heightened likelihood of further complications such as sepsis. That pattern, the hospital said, points to where early intervention and preventive care can make the most difference.

Chronic lung disease, clinically termed bronchopulmonary dysplasia, ranks among the gravest threats tied to prematurity. It surfaces in an estimated 30 to 45 percent of the most premature infants worldwide, a prevalence that has kept it at the center of neonatal research.

Within the Corniche cohort, whose average birth weight sat at just 885 grams (±283), the disease showed up across a spectrum of severity: 31.1 percent of cases were graded mild, 27.3 percent moderate, and 11.2 percent severe.

The retrospective review also pointed to how closely the unit followed international treatment standards. Antenatal steroids reached 95 percent of the mothers, while 84.5 percent of the babies received surfactant therapy—two interventions with a well-established record of improving how premature lungs perform.

Survival figures held up against international comparisons. The cohort’s mortality rate came in at 9.3 percent, a result the hospital described as favorable when measured against global data for comparably high-risk newborns.

Dr. Ihab Elkadry, a neonatologist at Corniche Hospital, framed the work in personal terms. “For every premature baby who takes their first breath, a new story of hope begins. Our goal is to protect the fragile lungs of these babies while supporting their growth and development. Watching a baby who once struggled for every breath leave the NICU breathing independently is one of the most rewarding moments for our entire team,” he said.

The hospital said the study is already reshaping practice across the SEHA network, feeding into stronger respiratory protocols, tighter infection controls, and more tightly coordinated work among specialist teams. Officials positioned the research as part of a wider push to standardize advanced maternal-fetal and neonatal care at scale, drawing on local data to sharpen interventions that have largely been guided by international benchmarks.